Prescribing drugs in Renal Failure: A Judicious Approach

Prescribing drugs in renal failure is essential to reduce their toxic effects due unusual accumulation failure. It because of less protein binding and prolong half life elimination case Usually the toxicity drug reduced by either diagnosing serum level specific or measuring eGFR particular patient. We commonly use three methods these cases side effect 1. Interval extension, 2. Dose reduction. 3. Combination above two. In patients on hemodialysis which are not bound easily eliminated, so such given after giving a fraction individual dose just hemodialysis. Renal Transplantation prescribing requires knowledge drug-drug interection. be remembered that get immediate therapeutic efficacy loading same as without failure, only maintenance with interval both. The following specially important during Failure NSAIDS Psyhotherapeutic Antimicrobials 4. Cardiovascular Drugs. Bangladesh J Medicine 2023; Vol. 34, No. 2(1) Supplement: 180